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Fibronectin, rat

CAT: 0579-FI24941-0.1Size: 0.1 mLDry Ice: NoHazardous: No
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CAT#:0579-FI24941-0.1Size:0.1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This antibody may be used to identify fibronectin during wound healing, during tumour progression, and tumour invasion respectively. Fibronectins are glycoproteins, which occur as dimers of two 200 kDa subunits. They have binding domains for bacterial proteins, collagens, heparin-like molecules and fibrin. Cellular fibronectin is widely distributed in the stroma of malignant tumours. Rat fibronectin 100%, rat collagen type I, II, III, IV and V <0.1%, rat elastin <0.1% (RIA at 1:5000 dilution).
UniProt
P04937 (FINC_Rat)
Host
Rabbit
Applications
IHC (paraffin), IF, ELISA, Radioimmunoassay, WB
Field of Research
Extracellular matrix
Purification Method
Affinity purified antibody lyophilized from phosphate buffered solution (non-sterile) Contains antimycotic substance, but no BSA and sodium azide! Reconstitute with 0,5 mL of sterile water and store aliquots at -20°C For further dilution use appropriate antibody diluent, eg Art No PU00,2 for IHC
Assay Principle
IHC(P), IFA, ELISA, RIA, IB (WB)
Concentration
1 mg/mL
Form
Affinity purified antibody lyophilized from phosphate buffered solution (non-sterile); Contains antimycotic substance, but; No BSA and sodium azide! Reconstitute with 0,5 mL of sterile water and store aliquots at -20°C; For further dilution use appropriate antibody diluent, e.g. Art; No; PU002 for IHC
References & Citations
1. Pankov R and Yamada KM (2002) Fibronectin at a glance. J Cell Sci. Oct 15;115(Pt 20):3861-3863. 2. Labat-Robert J (2002) Fibronectin in malignancy. Semin Cancer Biol. Jun;12(3):187-95.
Storage Conditions
-20°C