Yohimbic acid ethyl ester

• UNSPSC Description:

  Yohimbic acid ethyl ester (Compound 3a) is a selective ADRA2A antagonist with an IC50 of 31 nM[1].

• Target Antigen:

  Adrenergic Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/yohimbic-acid-ethyl-ester.html

• Smiles:

  O=C([C@@H]1[C@@]2([H])C[C@@]3([H])C4=C(CCN3C[C@]2([H])CC[C@@H]1O)C5=CC=CC=C5N4)OCC

• Molecular Weight:

  368.47

• References & Citations:

  [1]Chayka A, et al. Structure-Based Drug Design of ADRA2A Antagonists Derived from Yohimbine. J Med Chem. 2024 Jun 27;67(12):10135-10151.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  73840-32-1