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CHD4 Rabbit mAb [KD Validated] Antibody

CAT: 0013-GTR18302464-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18302464-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones.
Product Name Alternative
ATP dependent helicase CHD4; CHD4; Chromodomain helicase DNA binding protein 4; Mi 2 autoantigen 218 kDa protein; Mi 2b; Mi2 beta
UniProt
Q14839
Reactivity
Human
Immunogen
A synthesized peptide derived from human CHD4
Clonality
Monoclonal
Conjugation
Unconjugated
Source
Recombinant Rabbit
Field of Research
Epigenetics & Chromatin
Purification
Affinity-chromatography
Dilution
WB:1:1000~1:5000ICC/IF:1:50~1:200FC:1:50
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Molecular Weight
260kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
FC, ICC, WB
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · Q14839

ATP-dependent chromatin remodeler CHD4

CHD4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q14839
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CHD4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.6.4.-
Processing
—
Secondary accessions
Q8IXZ5
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingMetal-bindingNucleotide-bindingZinc

Molecular function

Chromatin regulatorDNA-bindingHydrolase

Cellular component

CytoplasmCytoskeletonNucleus

Disease

Disease variantIntellectual disability

Domain

RepeatZinc-finger

Biological process

TranscriptionTranscription regulation

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