SARS-CoV-2 nsp3-IN-1
CAT:
804-HY-150062-01
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
SARS-CoV-2 nsp3-IN-1
- CAS Number: 2892105-43-8
- UNSPSC Description: SARS-CoV-2 nsp3-IN-1 (Compound 15c) is a Mac1 (SARS-CoV-2 nsp3 macrodomain) inhibitor with the IC50 value of 6.1 μM. SARS-CoV-2 nsp3-IN-1 can inhibit Mac1 ADP-ribosylhydrolase activity. SARS-CoV-2 nsp3-IN-1 demonstrates notable selectivity for coronavirus macrodomains, especially towards SARS-CoV-2 Mac1[1].
- Target Antigen: SARS-CoV
- Type: Reference compound
- Related Pathways: Anti-infection
- Applications: COVID-19-anti-virus
- Field of Research: Infection
- Assay Protocol: https://www.medchemexpress.com/sars-cov-2-nsp3-in-1.html
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: OC([C@H](CC1=CNC2=C1C=CC=C2)NC3=NC=NC4=C3C=CN4)=O
- Molecular Weight: 321.33
- References & Citations: [1]Lavinia M Sherrill, et al. Design, Synthesis and Evaluation of Inhibitors of the SARS-CoV2 nsp3 Macrodomain. bioRxiv. 2022 Feb 28:2022.02.27.482176.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported