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Phospho-BRCA1 (Ser1423) polyclonal antibody

CAT: 0013-GTR18300584-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18300584-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Phospho-BRCA1 (Ser1423) polyclonal antibody
Product Name Alternative
BRCA1; RNF53; Breast cancer type 1 susceptibility protein; RING finger protein 53
UniProt
P38398
Reactivity
Human, Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human BRCA1 around the phosphorylation site of Ser1423. AA range:1391-1440
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Signal Transduction
Purification
Affinity Purified
Concentration
1mg/ml
Dilution
WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000
Form
Liquid in PBS containing 50% glycerol, 0.5% rAlbumin and 0.02% sodium azide, pH 7.3.
Molecular Weight
Calculated MW: 208 kDa; Observed MW: 208 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ELISA, IHC-P, WB
Host or Source
Rabbit
Preservative
Liquid in PBS containing 50% glycerol, 0.5% rAlbumin and 0.02% sodium azide, pH 7.3.

UniProtKB · P38398

Breast cancer type 1 susceptibility protein

BRCA1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P38398
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
BRCA1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.3.2.27
Processing
—
Secondary accessions
E9PFZ0, O15129, Q1RMC1, Q3LRJ0, Q3LRJ6, Q6IN79, Q7KYU9
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Molecular function

ActivatorDNA-bindingTransferase

Coding sequence diversity

Alternative initiationAlternative splicing

Biological process

Cell cycleDNA damageDNA recombinationDNA repairTranscriptionTranscription regulationUbl conjugation pathway

Cellular component

ChromosomeCytoplasmNucleus

Disease

Disease variantFanconi anemiaTumor suppressor

Ligand

Metal-bindingZinc

Domain

RepeatZinc-finger

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