3F8

• Description :

  3F8 is a potent and selective GSK-3β inhibitor that could be useful as new reagent and potential therapeutic candidate for GSK3 related diseases[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302

• Target :

  GSK-3

• Type :

  Reference compound

• Related Pathways :

  PI3K/Akt/mTOR; Stem Cell/Wnt

• Applications :

  Metabolism-sugar/lipid metabolism

• Field of Research :

  Cancer; Metabolic Disease; Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/3f8.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(N1)C2=C3C(C=C(OC)C(OC)=C3)=C(CC)N=C2C1=O

• Molecular Formula :

  C15H14N2O4

• Molecular Weight :

  286.28

• Precautions :

  P264-P270-P330-P501

• References & Citations :

  [1]Zhong H, et al. Characterization and development of novel small-molecules inhibiting GSK3 and activating Wnt signaling. Mol Biosyst. 2009 Nov;5 (11) :1356-60.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 2

• CAS Number :

  [159109-11-2]