γ-Neuropeptide (rabbit)

γ-Neuropeptide (rabbit)

• CAS Number: 114882-65-4
• UNSPSC Description: γ-Neuropeptide (rabbit) can be isolated from rabbit intestine. γ-Neuropeptide is an endogenous neurokinin peptide that acts as a neurokinin 2 (NK2) receptor agonist. γ-Neuropeptide mediates hypothalamic-pituitary-adrenal (HPA) axis, as well as reproductive hormone release[1][2][3].
• Target Antigen: Neurokinin Receptor
• Type: Peptides
• Related Pathways: GPCR/G Protein;Neuronal Signaling
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Endocrinology; Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/γ-neuropeptide-rabbit.html
• Solubility: 10 mM in DMSO
• Smiles: OC(C[C@H](N)C(N[C@@H](C)C(NCC(N[C@@H](CC1=CN=CN1)C(NCC(N[C@@H](CCC(N)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CO)C(N[C@@H](CC2=CN=CN2)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@@H](CCCCN)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(O)=O)C(N[C@@H](CO)C(N[C@H](C(N[C@@H](C(C)C)C(NCC(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)CCSC)=O)=O)=O)=O)CC3=CC=CC=C3)=O)=O)=O)=O)=O)CC4=CN=CN4)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
• Molecular Weight: 2320.59
• References & Citations: [1]Kage R, et al. Neuropeptide-gamma: a peptide isolated from rabbit intestine that is derived from gamma-preprotachykinin. J Neurochem. 1988 May;50(5):1412-7. |[2]Yuan L, et al. Characterization of tachykinin receptors mediating bronchomotor and vasodepressor responses to neuropeptide gamma and substance P in the anaesthetized rabbit. Pulm Pharmacol Ther. 1998 Feb;11(1):31-9. |[3]Debeljuk L, et al. Modulation of the hypothalamo-pituitary-gonadal axis and the pineal gland by neurokinin A, neuropeptide K and neuropeptide gamma. Peptides. 1999;20(2):285-99. |[4]Kalra PS, et al. Diverse effects of tachykinins on luteinizing hormone release in male rats: mechanism of action. Endocrinology. 1992 Sep;131(3):1195-201. |[5]Debeljuk L, et al. In vivo and in vitro effects of neuropeptide K and neuropeptide gamma on the release of growth hormone. Neuroreport. 1995 Dec 15;6(18):2457-60.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported