Products for Research Use Only
RegisterLogin

γ-Neuropeptide (rabbit)

CAT: 0804-HY-P3069-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-P3069-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
γ-Neuropeptide (rabbit) can be isolated from rabbit intestine. γ-Neuropeptide is an endogenous neurokinin peptide that acts as a neurokinin 2 (NK2) receptor agonist. γ-Neuropeptide mediates hypothalamic-pituitary-adrenal (HPA) axis, as well as reproductive hormone release[1][2][3].
CAS Number
114882-65-4
UNSPSC
12352209
Target
Neurokinin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/γ-neuropeptide-rabbit.html
Purity
99.99
Solubility
DMSO : 5 mg/mL (ultrasonic)
Smiles
OC(C[C@H](N)C(N[C@@H](C)C(NCC(N[C@@H](CC1=CN=CN1)C(NCC(N[C@@H](CCC(N)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CO)C(N[C@@H](CC2=CN=CN2)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@@H](CCCCN)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(O)=O)C(N[C@@H](CO)C(N[C@H](C(N[C@@H](C(C)C)C(NCC(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)CCSC)=O)=O)=O)=O)CC3=CC=CC=C3)=O)=O)=O)=O)=O)CC4=CN=CN4)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C99H158N34O29S
Molecular Weight
2320.59
References & Citations
[1]Kage R, et al. Neuropeptide-gamma: a peptide isolated from rabbit intestine that is derived from gamma-preprotachykinin. J Neurochem. 1988 May;50 (5) :1412-7. |[2]Yuan L, et al. Characterization of tachykinin receptors mediating bronchomotor and vasodepressor responses to neuropeptide gamma and substance P in the anaesthetized rabbit. Pulm Pharmacol Ther. 1998 Feb;11 (1) :31-9. |[3]Debeljuk L, et al. Modulation of the hypothalamo-pituitary-gonadal axis and the pineal gland by neurokinin A, neuropeptide K and neuropeptide gamma. Peptides. 1999;20 (2) :285-99. |[4]Kalra PS, et al. Diverse effects of tachykinins on luteinizing hormone release in male rats: mechanism of action. Endocrinology. 1992 Sep;131 (3) :1195-201. |[5]Debeljuk L, et al. In vivo and in vitro effects of neuropeptide K and neuropeptide gamma on the release of growth hormone. Neuroreport. 1995 Dec 15;6 (18) :2457-60.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
NK2R

Chemical Information

Tachykinin neuropeptide gamma

potentiates substance P-induced salivation; lacks residues (3-17) of neuropeptide K; derived from gamma-preprotachykinin

CAS Number114882-65-4
PubChem CID16132172
IUPAC Name(3S)-3-amino-4-[[(2S)-1-[[2-[[(2S)-1-[[2-[[(2S)-5-amino-1-[[(2S,3S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-2-oxoethyl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoic acid
Molecular FormulaC99H158N34O29S
Molecular Weight2320.6
XLogP-14
Topological Polar Surface Area1050
Hydrogen Bond Donor Count36
Hydrogen Bond Acceptor Count37
Rotatable Bond Count80
Heavy Atom Count163
Formal Charge0
Complexity4960
SMILES
CC[C@H](C)[C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC2=CN=CN2)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)NC(CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N)NC(=O)[C@H](CCC(=O)N)NC(=O)CNC(=O)[C@H](CC4=CN=CN4)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)N
InChI
InChI=1S/C99H158N34O29S/c1-10-51(6)79(132-88(152)63(24-25-72(103)137)118-73(138)42-112-84(148)66(33-55-38-107-46-114-55)120-74(139)41-111-82(146)52(7)117-83(147)58(102)36-76(141)142)97(161)130-71(45-135)95(159)127-68(35-57-40-109-48-116-57)91(155)123-60(21-14-16-27-100)85(149)122-62(23-18-29-110-99(105)106)86(150)126-67(34-56-39-108-47-115-56)90(154)124-61(22-15-17-28-101)87(151)133-80(53(8)136)98(162)128-69(37-77(143)144)92(156)129-70(44-134)94(158)125-65(32-54-19-12-11-13-20-54)93(157)131-78(50(4)5)96(160)113-43-75(140)119-64(31-49(2)3)89(153)121-59(81(104)145)26-30-163-9/h11-13,19-20,38-40,46-53,58-71,78-80,134-136H,10,14-18,21-37,41-45,100-102H2,1-9H3,(H2,103,137)(H2,104,145)(H,107,114)(H,108,115)(H,109,116)(H,111,146)(H,112,148)(H,113,160)(H,117,147)(H,118,138)(H,119,140)(H,120,139)(H,121,153)(H,122,149)(H,123,155)(H,124,154)(H,125,158)(H,126,150)(H,127,159)(H,128,162)(H,129,156)(H,130,161)(H,131,157)(H,132,152)(H,133,151)(H,141,142)(H,143,144)(H4,105,106,110)/t51-,52-,53+,58-,59-,60-,61-,62-,63-,64?,65-,66-,67-,68-,69-,70-,71-,78-,79-,80-/m0/s1
InChIKey
NISSWFHUIGHJLY-DKRDOARVSA-N
Chemical Structure
2D Structure
2D structure of Tachykinin neuropeptide gamma
CAS: 114882-65-4
CID: 16132172
Formula: C99H158N34O29S
MW: 2320.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight2320.6
XLogP3-14
Hydrogen Bond Donor Count36
Hydrogen Bond Acceptor Count37
Rotatable Bond Count80
Exact Mass2320.1688212
Monoisotopic Mass2319.1654663
Topological Polar Surface Area1050 Ų
Heavy Atom Count163
Formal Charge0
Complexity4960
Isotope Atom Count0
Defined Atom Stereocenter Count19
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-P2135Neuropeptide AF1
HY-P1248-01Neuropeptide FF
HY-P1716Neuropeptide DF2
HY-P1246Neuropeptide AF (human)
HY-P1438-01Neuropeptide S (Rat)
HY-P1400Neuropeptide Y (scrambled)
HY-P1245-01Neuropeptide SF (human)
HY-P3843Neuropeptide AF (cattle)
HY-P1869Neuropeptide EI, rat
HY-P1389-01Neuropeptide S (human)

Alternative Products

CatalogName
E-PP-0505-01┚-Neuropeptide, rabbit
5-00506γ-Neuropeptide, rabbit
MBS826569-01Gamma-Neuropeptide, Rabbit
350207Neuropeptide Gamma (Rabbit)
GTR10409237Rabbit Neuropeptide A ELISA
abx266880-01Gamma Neuropeptide, rabbit
APA3364-01Neuropeptide Y Rabbit pAb
MBS750344-01Rabbit Neuropeptide A ELISA Kit
E47R19221Neuropeptide Q Rabbit pAb
E47R11422Neuropeptide S Rabbit pAb

Popular Products