(±) -Perillaldehyde

• Description :

  (±) -Perillaldehyde has an antidepressant effect by modulating the olfactory nervous system in a mouse model of stress-induced depression. (±) -Perillaldehyde also has anti-inflammatory activity, inducing JNK activation in RAW264.7 cells and inhibiting the expression of TNF-α, with an IC50 of 171.7 μM[1][2].

• UNSPSC :

  12352211

• Hazard Statement :

  H315, H319, H335

• Target :

  JNK; TNF Receptor

• Type :

  Reference compound

• Related Pathways :

  Apoptosis; MAPK/ERK Pathway

• Field of Research :

  Inflammation/Immunology; Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/racemic-perillaldehyde.html

• Purity :

  96.70

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  CC(C1CCC(C=O)=CC1)=C

• Molecular Formula :

  C10H14O

• Molecular Weight :

  150.22

• Precautions :

  H315, H319, H335

• References & Citations :

  [1]N Ito, et al. Antidepressant-like Effect of l-perillaldehyde in Stress-induced Depression-like Model Mice through Regulation of the Olfactory Nervous System. Evid Based Complement Alternat Med. 2011:2011:512697.|[2]Takuya Uemura, et al. Intestinal Anti-Inflammatory Activity of Perillaldehyde. J Agric Food Chem. 2018 Apr 4;66 (13) :3443-3448.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2111-75-3]