N 0861

CAT: 0804-HY-105093-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-105093-01Size:1 mg
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Description
N-0861 is a novel selective A1 adenosine receptor antagonist. In studies, it has been shown to be able to inhibit the negative conduction effects (prolonged AH interval) and chest pain caused by adenosine, while having no significant effect on the increase in coronary blood flow velocity caused by adenosine. This indicates that N-0861 has the property of selectively inhibiting A1 adenosine receptors[1].
CAS Number
[141696-90-4]
UNSPSC
12352005
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/n-0861.html
Smiles
CN(C=N1)C2=C1C(N[C@H]3[C@@H]4C[C@@H](CC4)C3)=NC=N2
Molecular Formula
C13H17N5
Molecular Weight
243.31
References & Citations
[1]Bertolet BD, et al. Selective attenuation by N-0861 (N6-endonorboran-2-yl-9-methyladenine) of cardiac A1 adenosine receptor-mediated effects in humans. Circulation. 1996 May 15;93 (10) :1871-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3

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