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CCDC98 Rabbit mAb [KD Validated] Antibody

CAT: 0013-GTR18302257-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18302257-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs) .
Product Name Alternative
ABRA1; ABRAXAS; FAM175A
UniProt
Q6UWZ7
Reactivity
Human
Immunogen
A synthesized peptide derived from human CCDC98
Clonality
Monoclonal
Conjugation
Unconjugated
Source
Recombinant Rabbit
Field of Research
Epigenetics & Chromatin
Purification
Affinity-chromatography
Dilution
WB:1:500~1:2000ICC/IF:1:50~1:200IP:1:50FC:1:50
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Molecular Weight
50kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
FC, ICC, IP, WB
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · Q6UWZ7

BRCA1-A complex subunit Abraxas 1

ABRX1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q6UWZ7
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ABRAXAS1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A5JJ07, Q9H8I1, Q9H9N4
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Molecular function

Chromatin regulator

Domain

Coiled coil

Disease

Disease variant

Biological process

DNA damageDNA repair

Cellular component

Nucleus

PTM

Phosphoprotein

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