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Phospho-c-Abl-Y412 polyclonal antibody

CAT: 0013-GTR18297839-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18297839-01Size:50 µL
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Description
Phospho-c-Abl-Y412 polyclonal antibody
Product Name Alternative
ABL; JTK7; p150; c-ABL; v-abl; CHDSKM; c-ABL1; ABL1; c-Abl; bcr/abl
UniProt
P00519
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic phosphorylated peptide around Y412 of human ABL1 (NP_005148.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cell Biology
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1mg/ml
Dilution
WB,1:500 - 1:2000|IHC,1:50 - 1:200
Form
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH 7.2
Molecular Weight
123kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
IHC, WB
Host or Source
Rabbit
Preservative
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH 7.2

UniProtKB · P00519

Tyrosine-protein kinase ABL1

ABL1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P00519
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ABL1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.10.2
Processing
—
Secondary accessions
A3KFJ3, Q13869, Q13870, Q16133, Q17R61, Q45F09
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationLipoproteinMyristatePhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicingChromosomal rearrangement

Biological process

ApoptosisAutophagyCell adhesionDNA damageDNA repairEndocytosis

Ligand

ATP-bindingMagnesiumManganeseMetal-bindingNucleotide-binding

Cellular component

CytoplasmCytoskeletonMembraneMitochondrionNucleus

Disease

Disease variantProto-oncogene

Molecular function

DNA-bindingKinaseTransferaseTyrosine-protein kinase

Domain

SH2 domainSH3 domain

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