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DNMT1 polyclonal antibody

CAT: 0013-GTR18295102-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18295102-02Size:100 µL
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Description
DNMT1 polyclonal antibody
Product Name Alternative
ADCADN; AIM; CXXC9; DNMT; HSN1E; MCMT; m.HsaI; DNMT1
UniProt
P26358
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human DNMT1 (NP_001370.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Epigenetics & Chromatin
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1mg/ml
Dilution
WB,1:500 - 1:2000|IHC,1:50 - 1:200|IF/ICC,1:50 - 1:200|IP,1:50 - 1:200
Form
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH 7.2
Molecular Weight
200KDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
IF, IHC, IP, WB
Host or Source
Rabbit
Preservative
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH 7.2

UniProtKB · P26358

DNA (cytosine-5)-methyltransferase 1

DNMT1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P26358
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
DNMT1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Dnmt1
EC number
2.1.1.37
Processing
—
Secondary accessions
A0AV63, B7ZLW6, Q9UHG5, Q9ULA2, Q9UMZ6
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondMethylationPhosphoproteinUbl conjugation

Molecular function

ActivatorChromatin regulatorDNA-bindingMethyltransferaseRepressorTransferase

Coding sequence diversity

Alternative splicing

Cellular component

ChromosomeNucleus

Disease

DeafnessDisease variantNeuropathy

Ligand

Metal-bindingS-adenosyl-L-methionineZinc

Domain

RepeatZinc-finger

Biological process

TranscriptionTranscription regulation

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