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Ex26

CAT: 0804-HY-117213-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-117213-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ex26 (S1P1-IN-Ex26) is a potent and selective sphingosine 1-phosphate receptor 1 (S1P1) antagonist (IC50=0.93 nM) . Ex26 shows >3,000-fold selectivity for S1P1 over other Sphingosine 1-phosphate receptors. Ex26 can be used in experimental autoimmune encephalomyelitis reseach[1].
CAS Number
1233332-37-0
Product Name Alternative
S1P1-IN-Ex26
UNSPSC
12352005
Target
LPL Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ex26.html
Purity
99.4
Solubility
10 mM in DMSO
Smiles
O=C(O)C1(CC1)NC(C2=C(C=C(C=C2C)C3=CC(NC(C)C4=CC=C(C(C)=C4)Cl)=CC=C3F)C)=O
Molecular Formula
C28H28ClFN2O3
Molecular Weight
494.98
References & Citations
[1]Stuart M Cahalan, et al. Sphingosine 1-phosphate receptor 1 (S1P (1) ) upregulation and amelioration of experimental autoimmune encephalomyelitis by an S1P (1) antagonist. Mol Pharmacol. 2013 Feb;83 (2) :316-21.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
BA5482-5Ex26
MBS5778320S1P1-IN-Ex26

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