DIAP2 rabbit pAb

• Background:

  The product of this gene belongs to the diaphanous subfamily of the formin homology family of proteins. This gene may play a role in the development and normal function of the ovaries. Defects in this gene have been linked to premature ovarian failure 2. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

• Description:

  The product of this gene belongs to the diaphanous subfamily of the formin homology family of proteins. This gene may play a role in the development and normal function of the ovaries. Defects in this gene have been linked to premature ovarian failure 2. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],

• Synonyms:

  Protein diaphanous homolog 2 (Diaphanous-related formin-2;DRF2)

• Gene ID:

  1730

• UniProt:

  O60879

• Cellular Locus:

  [Isoform 3]: Cytoplasm, cytosol. Early endosome. Isoform 3 is cytosolic but when coexpressed with RHOD, the 2 proteins colocalize to early endosomes.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse

• Reactivity:

  Human; Mouse

• Immunogen:

  Synthesized peptide derived from human DIAP2

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  IHC; IF; WB

• Validated Applications:

  IHC, IF, WB

• Stability:

  -20°C / 1 year

• Concentration:

  1 mg/mL

• Dilution:

  IHC-p 1:50-200, WB 1:500-2000

• Molecular Weight:

  125kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  125kD

• Subcellular Location:

  [Isoform 3]: Cytoplasm, cytosol. Early endosome. Isoform 3 is cytosolic but when coexpressed with RHOD, the 2 proteins colocalize to early endosomes.

• Other Product Names:

  Protein diaphanous homolog 2 (Diaphanous-related formin-2; DRF2)

• Gene ID (Human):

  1730

• SwissProt (Human):

  O60879