ULK1-IN-3

• UNSPSC Description:

  ULK1-IN-3 (Compound 8) is a novel chromone-based as a potential inhibitor of ULK1. ULK1-IN-3 inhibits cell cycle, autophagy and induces apoptosis, oxidative stress in colon cancer cell lines[1].

• Target Antigen:

  Akt; AMPK; Apoptosis; Autophagy; NF-κB; PARP; Reactive Oxygen Species; ULK

• Type:

  Reference compound

• Related Pathways:

  Apoptosis;Autophagy;Cell Cycle/DNA Damage;Epigenetics;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB;PI3K/Akt/mTOR

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/ulk1-in-3.html

• Smiles:

  COC1=CC=C(C(C(C2=CC=C(CCl)C=C2)=C(C3=CC=C(OC)C(OC)=C3)O4)=O)C4=C1

• Molecular Weight:

  436.88

• References & Citations:

  [1]Shamsudin NF, et al. A novel chromone-based as a potential inhibitor of ULK1 that modulates autophagy and induces apoptosis in colon cancer. Future Med Chem. 2024 Jul 1:1-19.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported