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BACE1 Antibody

CAT: 0864-A21606-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0864-A21606-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Aliases
APP beta secretase, Asp 2, ASP2, Aspartyl protease 2, BACE 1, BACE, BACE1, BACE1_HUMAN, Beta secretase 1, Beta secretase, Beta site amyloid beta A4 precursor protein cleaving enzyme, Beta site amyloid precursor protein cleaving enzyme 1 , Beta site amyloid precursor protein cleaving enzyme, Beta site APP cleaving enzyme 1, Beta site APP cleaving enzyme, Beta-secretase 1, Beta-site amyloid precursor protein cleaving enzyme 1, Beta-site APP cleaving enzyme 1, FLJ90568, HSPC104, Memapsin 2, Memapsin-2, Memapsin2, Membrane associated aspartic protease 2, Membrane-associated aspartic protease 2, Transmembrane aspartic proteinase Asp2
UniProt
P56817
Host
Rabbit
Antigen Species
Human
Reactivity
Human, Mouse, Rat
Target Antigen
Synthesized peptide derived from Human BACE around the non-phosphorylation site of S498.
Target
BACE1
Clonality
Polyclonal
Conjugation
Non-conjugated
Applications
IHC, IF, ELISA, IHC:1:100-1:300, IF:1:200-1:1000, ELISA:1:5000
Field of Research
Neuroscience
Purification Method
Antigen affinity purified
Form
Liquid
Buffer
PBS, 50% glycerol, 0.5% BSA, 0.02% sodium azide, pH 7.4.
Storage Conditions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Fragment
IgG

UniProtKB · P56817

Beta-secretase 1

BACE1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P56817
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
BACE1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.4.23.46
Processing
Precursor
Secondary accessions
A0M8W7, B0YIU9, E9PE65, H7BXJ9, Q9BYB9, Q9BYC0, Q9BYC1, Q9UJT5, Q9ULS1
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationDisulfide bondGlycoproteinIsopeptide bondLipoproteinPalmitatePhosphoproteinUbl conjugationZymogen

Coding sequence diversity

Alternative splicing

Molecular function

Aspartyl proteaseHydrolaseProtease

Cellular component

Cell membraneCell projectionCytoplasmic vesicleEndoplasmic reticulumEndosomeGolgi apparatusLysosomeMembrane

Domain

SignalTransmembraneTransmembrane helix

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