Isoprothiolane

• Description:

  Isoprothiolane is a blast fungicide with antifungal, anti-inflammatory and insecticidal activities. Isoprothiolane primarily acts on fungi during the penetration and growth stages of infecting hyphae. Isoprothiolane can be used as an insecticide, pesticide, etc. In addition, Isoprothiolane can reduce serum phospholipid and total lipid concentrations, regulating lipid metabolism. Isoprothiolane is also used in the research of fatty liver[1][2][3][4].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Fungal; Interleukin Related; Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection; Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection; Metabolic Disease; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/isoprothiolane.html

• Purity:

  99.91

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C(OC(C)C)/C(C(OC(C)C)=O)=C1SCCS\1

• Molecular Formula:

  C12H18O4S2

• Molecular Weight:

  290.40

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Matazaemon Uchida, et al. Effect of a Rice Blast Controlling Agent, Isoprothiolane, on Nilaparvata Lugens Stal with Different Levels of Susceptibility to Diazinon. Pest Resistance to Pesticides pp 421-428|[2]Okada H, et al. Effects of isoprothiolane on cell growth of cultured bovine mammary epithelial cells. J Vet Med Sci. 1999 May;61 (5) :553-6.|[3]Kazuo K, et al . Effect of isoprothiolane on fatty acid synthesis. Journal of Pesticide Science, 1979, 4 (3) : 305-313.|[4]Tsuda T, et al. Acute toxicity, accumulation, and excretion of benthiocarb and its degradation products in killifish. Bull Environ Contam Toxicol. 1997 Apr;58 (4) :603-10.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  IL-1; IL-6

• CAS Number:

  [50512-35-1]