Products for Research Use Only
RegisterLogin

ITF 3756

CAT: 0804-HY-156850-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-156850-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
ITF 3756 is a potent and selective HDAC6 inhibitor. ITF 3756 reduces in vitro the expression of PD-L1 on human monocytes and on CD8 T cells, and shows anti-tumor activity[1].
CAS Number
2247608-27-9
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/itf-3756.html
Purity
98.55
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(CN2N=NN=C2C3=CC=CS3)C=C1)NO
Molecular Formula
C13H11N5O2S
Molecular Weight
301.32
References & Citations
[1]Gianluca Fossati, et al. Abstract 1358: The selective HDAC6 inhibitor ITF3756 stimulates an antitumor immune response and leads to tumor regression in combination with anti CTLA-4 antibody in a colon carcinoma murine model. Cancer Res (2022) 82 (12_Supplement) : 1358.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-123621-01GNE-375
HY-100332CP 375
HY-P70584-01Serpin F1, Mouse (375a.a)
HY-W952975CRBN ligand-375
HY-R00835-01Hsa-miR-375-5p mimic
HY-R00835A-01Hsa-miR-375-5p agomir
HY-RI00835-01Hsa-miR-375-5p inhibitor
HY-R00834A-01Hsa-miR-375-3p agomir
HY-RI03106-01Mmu-miR-375-5p inhibitor
HY-R00834-01Hsa-miR-375-3p mimic

Alternative Products

CatalogName
A24025-100ITF 3756 100mg
A24025-5ITF 3756 5mg
A24025-50ITF 3756 50mg
A24025-10ITF 3756 10mg
SR302525KCNH1 Human siRNA Oligo Duplex (Locus ID 3756)
TR303828KCNH1 Human shRNA Plasmid Kit (Locus ID 3756)
TL303828VKCNH1 Human shRNA Lentiviral Particle (Locus ID 3756)

Popular Products