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CCT070535

CAT: 0804-HY-164467Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-164467Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CCT070535 blocks TCF-dependent transcription at the TCF level, with GI50 values of 17.6 μM, 11.1 μM, 11.8 μM and 13.4 μM in HT29 (APC mutant), HCT116 (oncogenic β-catenin), SW480 (APC mutant) and SNU475 (Axin mutant) cells, respectively[1].
CAS Number
485319-41-3
UNSPSC
12352005
Target
Wnt
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cct070535.html
Smiles
O=C1C(CC2=CC=CC=C2)=C([O-])[N+]3=NC(Cl)=CC=C3N1C4=CC=C(Cl)C=C4
Molecular Formula
C20H13Cl2N3O2
Molecular Weight
398.24
References & Citations
[1]Kenneth Ewan, et al. A useful approach to identify novel small-molecule inhibitors of Wnt-dependent transcription. Cancer Res. 2010 Jul 15;70 (14) :5963-73.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
T200294-01CCT070535

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