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CAA-0225

CAT: 0804-HY-16121Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-16121Size:1 Each
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Description
CAA-0225 is a tissue protease L inhibitor that inhibits rat liver tissue protease L with a IC50 value of 1.9 nM. CAA-0225 can participate in the degradation of autophagosome membrane markers LC3-II and GABARAP , improve cardiac function in mice with reperfusion injury, and kill and eliminate Trypanosoma brucei parasites[1][2][3].
CAS Number
244072-26-2
UNSPSC
12352005
Target
Cathepsin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/caa-0225.html
Smiles
O=C([C@H]1O[C@@H]1C(N[C@@H](CC2=CC=CC=C2)C(NCC3=CC=CC=C3)=O)=O)NCCC4=CC=C(O)C=C4
Molecular Formula
C28H29N3O5
Molecular Weight
487.55
References & Citations
[1]Characterization of CAA0225, a Novel Inhibitor Specific for Cathepsin L, as a Probe for Autophagic Proteolysis
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
Cathepsin L

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