Spiramycin III

• Description:

  Spiramycin III (SPMIII) is a main component of Spiramycin. Spiramycin (HY-100593) is a macrolide antibiotic produced by Streptomyces ambofaciens with against bacteria and Toxoplasma gondii activities, and also has antiparasitic effect[1][2].

• UNSPSC:

  12352005

• Target:

  Antibiotic; Bacterial; Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/spiramycin-iii.html

• Smiles:

  C[C@@H]1[C@H](CC[C@@H](O1)O[C@@H]2[C@@H](C[C@@H]([C@@H]([C@@H](OC)[C@@H](CC(O[C@H](C)C/C=C\C=C\2)=O)OC(CC)=O)O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)N(C)C)O[C@@H]4O[C@H]([C@@H]([C@@](C)(C4)O)O)C)C)CC=O)C)N(C)C

• Molecular Formula:

  C46H78N2O15

• Molecular Weight:

  899.12

• References & Citations:

  [1]X R Xu, et al. [Determination of partition coefficient by high-pressure liquid chromatography. I. Determination of partition coefficient of cinnamic acids and related compounds by reversed-phase high-pressure liquid chromatography (author's transl) ]. Yao Xue Xue Bao. 1979;14 (4) :246-52. |[2]Nguyen HC, et al. Post-PKS tailoring steps of the spiramycin macrolactone ring in Streptomyces ambofaciens. Antimicrob Agents Chemother. 2013 Aug;57 (8) :3836-42.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• Isoform:

  Macrolide

• CAS Number:

  24916-52-7