Products for Research Use Only
RegisterLogin

Sotalol

CAT: 0804-HY-103196Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-103196Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Sotalol is an orally active, non-selective β-adrenergic receptor blocker. Sotalol is a potent antiarrhythmic agent that can be used for the research of pediatric arrhythmias. Sotalol blocks β-receptors, and potassium KCNH2 channels. Antiepileptic Agent[1][2][3].
CAS Number
3930-20-9
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Adrenergic Receptor; Potassium Channel
Type
Reference compound
Related Pathways
GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/sotalol.html
Solubility
10 mM in DMSO
Smiles
CS(=O)(NC1=CC=C(C(O)CNC(C)C)C=C1)=O
Molecular Formula
C12H20N2O3S
Molecular Weight
272.36
Precautions
P261-P280-P302+P352
References & Citations
[1]Marta Reyes-Corral, et al. Differential Free Intracellular Calcium Release by Class II Antiarrhythmics in Cancer Cell Lines. J Pharmacol Exp Ther. 2019 Apr;369 (1) :152-162.|[2]Xiaomei Li, et al. Pediatric Dosing of Intravenous Sotalol Based on Body Surface Area in Patients with Arrhythmia. Pediatr Cardiol. 2017 Oct;38 (7) :1450-1455.|[3]Kinga K Borowicz-Reutt, et al. Sotalol does not interfere with the antielectroshock action of selected second-generation antiepileptic drugs in mice.Pharmacol Rep. 2021 Apr;73 (2) :516-524.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
β adrenergic receptor

Alternative Products

CatalogName
B1367-100Sotalol
MBS5774695-01(-)-Sotalol
T72980(+) -Sotalol
FS61454-01Sotalol HCl
T0483-01Sotalol hydrochloride
AR-S10682-01Sotalol-d6

Popular Products