AAA

• UNSPSC Description:

  AAA is a potent blocker of 20-Hydroxyeicosatetraenoic acid (20-HETE) receptor that binds directly to GPR75 and prevents the increases in intracellular Ca2+, IP-1 and β-arrestin[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/aaa.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C([C@@H](NC(CCCC/C=C\CCCCCCC/C=C\CCCCO)=O)CC(O[Na])=O)O[Na]

• Molecular Weight:

  483.55

• References & Citations:

  [1]Jonathan V. Pascale, et al. 20-Hydroxyeicosatetraenoic acid (20-HETE): Bioactions, receptors, vascular function, cardiometabolic disease and beyond. Adv Pharmacol. 2023; 97: 229–255.

• Shipping Conditions:

  Blue Ice

• Clinical Information:

  Phase 4