Peraquinsin

CAT: 0804-HY-W726640-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-W726640-01Size:5 mg

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Description

Peraquinsin is a MK2 activator. Peraquinsin can be used for the research of vascular disorder or endothelial barrier disorder. Peraquinsin also is an antihypertensive agent[1].

CAS Number

35265-50-0

UNSPSC

12352005

Target

MAPKAPK2 (MK2)

Type

Reference compound

Related Pathways

MAPK/ERK Pathway

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/peraquinsin.html

Purity

98.65

Solubility

10 mM in DMSO

Smiles

O=C1N=C(CCN2CCN(CC2)C3=C(OC)C=CC=C3)NC4=CC(OC)=C(C=C14)OC

Molecular Formula

C23H28N4O4

Molecular Weight

424.49

References & Citations

[1]Katya TSAIOUN, et al. Mk2 activating compounds for use in treating vascular leak and endothelial barrier disorders. Patent. WO2022104097A2.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Chemical Information

Peraquinsin

Peraquinsin is a small molecule drug. Peraquinsin has a monoisotopic molecular weight of 424.21 Da.

CAS Number	35265-50-0
PubChem CID	135474663
IUPAC Name	6,7-dimethoxy-2-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-3H-quinazolin-4-one
Molecular Formula	C23H28N4O4
Molecular Weight	424.5
XLogP	2.2
Topological Polar Surface Area	75.6
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	7
Heavy Atom Count	31
Formal Charge	0
Complexity	637

SMILES

COC1=CC=CC=C1N2CCN(CC2)CCC3=NC4=CC(=C(C=C4C(=O)N3)OC)OC

InChI

InChI=1S/C23H28N4O4/c1-29-19-7-5-4-6-18(19)27-12-10-26(11-13-27)9-8-22-24-17-15-21(31-3)20(30-2)14-16(17)23(28)25-22/h4-7,14-15H,8-13H2,1-3H3,(H,24,25,28)

InChIKey

CSNKNIWBSXUJRO-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 35265-50-0

CID: 135474663

Formula: C23H28N4O4

MW: 424.5

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	424.5
XLogP3	2.2
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	7
Exact Mass	424.21105539
Monoisotopic Mass	424.21105539
Topological Polar Surface Area	75.6 Å²
Heavy Atom Count	31
Formal Charge	0
Complexity	637
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Alternative Products

Catalog	Name
T87129-01	Peraquinsin

Peraquinsin

Chemical Information

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