N4Py

CAT: 0804-HY-120420Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-120420Size:1 Each

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Description

N4Py is a pentadentate ligand, that forms a stable complex with metal ions, such as iron, platinum, and copper. N4py mimics the metal binding domains of iron-dependent antibiotics like Bleomycin , forms the DNA-cleaving FeII-N4Py complexes, generates reactive oxygen species (ROS), and causes oxidative damage in cells. N4py can be used in cancer research[1].

CAS Number

167695-87-6

UNSPSC

12352005

Target

Antibiotic

Type

Reference compound

Related Pathways

Anti-infection

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n4py.html

Smiles

C1(C(C2=CC=CC=N2)N(CC3=CC=CC=N3)CC4=NC=CC=C4)=NC=CC=C1

Molecular Formula

C23H21N5

Molecular Weight

367.45

References & Citations

[1]Geersing A, et al., Importance of Metal-Ion Exchange for the Biological Activity of Coordination Complexes of the Biomimetic Ligand N4Py. Inorg Chem. 2018 Jul 2;57 (13) :7748-7756.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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