CB2 receptor agonist 3

CB2 receptor agonist 3

• CAS Number: 919077-81-9
• UNSPSC Description: CB2 receptor agonist 3 is a robust and selective CB2 cannabinoid agonist with Kis of 7.6 and 900 nM for CB2 and CB1, respectively. CB2 receptor agonist 3 significantly increases P-ERK 1/2 expression in HL-60 cells[1].
• Target Antigen: Cannabinoid Receptor
• Type: Reference compound
• Related Pathways: GPCR/G Protein;Neuronal Signaling
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/cb2-receptor-agonist-3.html
• Purity: 99.86
• Solubility: DMSO : 12.5 mg/mL (ultrasonic;warming;heat to 60°C)
• Smiles: O=C(C1=NN(C2=C1CC3=C2C=CC(C)=C3)C4=CC=C(C=C4Cl)Cl)NC5CCCCC5
• Molecular Weight: 440.36
• References & Citations: [1]Murineddu G, et al. Tricyclic pyrazoles. 4. Synthesis and biological evaluation of analogues of the robust and selective CB2 cannabinoid ligand 1-(2',4'-dichlorophenyl)-6-methyl-N-piperidin-1-yl-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxamide. J Med Chem. 2006;49(25):7502-7512.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported