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Hippadine

CAT: 0804-HY-127152Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-127152Size:1 Each
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Description
Hippadine (Pratorine) is an alkaloid, which can be isolated from the plant Crinum macowanii. Hippadine exhibits heart-rate lowering and blood-pressure lowering effects in rats models with spontaneously hypertensive[1].
CAS Number
52886-06-3
Product Name Alternative
Pratorine
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/hippadine.html
Smiles
O=C1N2C3=C(C=CC=C3C4=C1C=C5C(OCO5)=C4)C=C2
Molecular Formula
C16H9NO3
Molecular Weight
263.25
References & Citations
[1]Mugabo P, et al., Effects of hippadine on the blood pressure and heart rate in male spontaneously hypertensive Wistar rats. J Ethnopharmacol. 2014 Dec 2;158 Pt A:123-31.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

Chemical Information

7H-(1,3)Dioxolo(4,5-j)pyrrolo(3,2,1-de)phenanthridin-7-one

Hippadine has been reported in Pancratium maritimum, Crinum latifolium, and other organisms with data available.

CAS Number52886-06-3
PubChem CID100605
IUPAC Name5,7-dioxa-12-azapentacyclo[10.6.1.02,10.04,8.015,19]nonadeca-1(18),2,4(8),9,13,15(19),16-heptaen-11-one
Molecular FormulaC16H9NO3
Molecular Weight263.25
XLogP3.1
Topological Polar Surface Area40.5
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count0
Heavy Atom Count20
Formal Charge0
Complexity439
SMILES
C1OC2=C(O1)C=C3C(=C2)C4=CC=CC5=C4N(C3=O)C=C5
InChI
InChI=1S/C16H9NO3/c18-16-12-7-14-13(19-8-20-14)6-11(12)10-3-1-2-9-4-5-17(16)15(9)10/h1-7H,8H2
InChIKey
DONUVZIVKLIMJU-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 7H-(1,3)Dioxolo(4,5-j)pyrrolo(3,2,1-de)phenanthridin-7-one
CAS: 52886-06-3
CID: 100605
Formula: C16H9NO3
MW: 263.25
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight263.25
XLogP33.1
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count0
Exact Mass263.058243149
Monoisotopic Mass263.058243149
Topological Polar Surface Area40.5 Ų
Heavy Atom Count20
Formal Charge0
Complexity439
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
GTR19260020-01Hippadine

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