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Oryzalin

CAT: 0804-HY-147092-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-147092-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Oryzalin is a dinitroaniline herbicide with antimitotic and antileishmanial activities. Oryzalin can bind to plant tubulin, inhibit the polymerization of microtubules in plant cells, and affect chromosome migration. Oryzalin can also be used to induce chromosome doubling[1][2][3].
CAS Number
19044-88-3
UNSPSC
12352005
Hazard Statement
H350, H360, H411
Target
Herbicide; Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/oryzalin.html
Concentration
10mM
Purity
99.62
Solubility
DMSO : 233.33 mg/mL (ultrasonic)
Smiles
O=S(C1=CC([N+]([O-])=O)=C(N(CCC)CCC)C([N+]([O-])=O)=C1)(N)=O
Molecular Formula
C12H18N4O6S
Molecular Weight
346.36
Precautions
H350, H360, H411
References & Citations
[1]Morejohn LC, et al. Oryzalin, a dinitroaniline herbicide, binds to plant tubulin and inhibits microtubule polymerization in vitro. Planta. 1987 Oct;172 (2) :252-64.|[2]Bouvier L, et al. Oryzalin as an efficient agent for chromosome doubling of haploid apple shoots in vitro. Plant Breeding, 1994, 113 (4) : 343-346.|[3]Lopes RM, et al. Formulation of oryzalin (ORZ) liposomes: in vitro studies and in vivo fate. Eur J Pharm Biopharm. 2012 Oct;82 (2) :281-90.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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