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QGC583

CAT: 0804-HY-162920Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-162920Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
QGC583 is an effective selective Aminopeptidase A (APA) inhibitor with oral activity and blood-brain barrier permeability, boasting an IC50 value of 4 nM. QGC583 can inhibit APA activity in the brain, kidneys, and heart of rats[1].
CAS Number
2417001-25-1
UNSPSC
12352211
Target
Aminopeptidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/qgc583.html
Smiles
O=P([C@@H](N)CCC(O)=O)(O)CCC1=C(OC)C=CC=C1
Molecular Formula
C13H20NO5P
Molecular Weight
301.28
References & Citations
[1]Balavoine F, et al. Rational design, synthesis and pharmacological characterization of novel aminopeptidase A inhibitors[J]. Bioorganic & Medicinal Chemistry Letters, 2024, 113: 129940.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
GTR19238747-01QGC583

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