Acacetin 7-O-(6-O-malonylglucoside)

Acacetin 7-O-(6-O-malonylglucoside)

• CAS Number: 155049-92-6
• UNSPSC Description: Acacetin 7-O-(6-O-malonylglucoside) is a monoamine oxidase inhibitor with strong inhibitory effects on monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B) with IC50 values ​​of 2.34 and 1.87 μM, respectively. Acacetin 7-O-(6-O-malonylglucoside) is a reversible MAO inhibitor that can be used in the research of neurodegenerative diseases and affective disorders[1].
• Target Antigen: Monoamine Oxidase
• Type: Natural Products
• Related Pathways: Neuronal Signaling
• Applications: Neuroscience-Neurodegeneration
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/acacetin-7-o-6-o-malonylglucoside.html
• Smiles: O=C1C2=C(O)C=C(O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)COC(CC(O)=O)=O)C=C2OC(C4=CC=C(C=C4)OC)=C1
• Molecular Weight: 532.45
• References & Citations: [1]Lee H W, et al. Potent inhibitions of monoamine oxidase A and B by acacetin and its 7-O-(6-O-malonylglucoside) derivative from Agastache rugosa[J]. International journal of biological macromolecules, 2017, 104: 547-553.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported