Acacetin 7-O-(6-O-malonylglucoside)

• UNSPSC Description:

  Acacetin 7-O-(6-O-malonylglucoside) is a monoamine oxidase inhibitor with strong inhibitory effects on monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B) with IC50 values ​​of 2.34 and 1.87 μM, respectively. Acacetin 7-O-(6-O-malonylglucoside) is a reversible MAO inhibitor that can be used in the research of neurodegenerative diseases and affective disorders[1].

• Target Antigen:

  Monoamine Oxidase

• Type:

  Natural Products

• Related Pathways:

  Neuronal Signaling

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/acacetin-7-o-6-o-malonylglucoside.html

• Smiles:

  O=C1C2=C(O)C=C(O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)COC(CC(O)=O)=O)C=C2OC(C4=CC=C(C=C4)OC)=C1

• Molecular Weight:

  532.45

• References & Citations:

  [1]Lee H W, et al. Potent inhibitions of monoamine oxidase A and B by acacetin and its 7-O-(6-O-malonylglucoside) derivative from Agastache rugosa[J]. International journal of biological macromolecules, 2017, 104: 547-553.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  155049-92-6