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Arachidonylcyclopropylamide

CAT: 0804-HY-110003Size: 5 mg (145.54 mM x 100 μL in Ethanol)Dry Ice: NoHazardous: No
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CAT#:0804-HY-110003Size:5 mg (145.54 mM x 100 μL in Ethanol)
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Description
Arachidonylcyclopropylamide (ACPA) is a potent and selective CB1 receptors agonist. Arachidonylcyclopropylamide inhibits forskolin-stimulated cAMP production in CHO cells transfected with human cannabinoid CB1 receptors (IC50=2 nM) [1].
CAS Number
229021-64-1
Product Name Alternative
ACPA
UNSPSC
12352211
Hazard Statement
H225, H319
Target
Cannabinoid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/arachidonylcyclopropylamide.html
Concentration
145.54 mM * 100 μL in Ethanol
Purity
99.9
Solubility
10 mM in DMSO
Smiles
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(NC1CC1)=O
Molecular Formula
C23H37NO
Molecular Weight
343.55
Precautions
H225, H319
References & Citations
[1]Franklin A, et al. Arachidonylcyclopropylamide increases microglial cell migration through cannabinoid CB2 and abnormal-cannabidiol-sensitive receptors. Eur J Pharmacol. 2003;474 (2-3) :195-198.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

Arachidonylcyclopropylamide

a potent and selective agonist of neuronal cannabinoid receptor; structure in first source

CAS Number229021-64-1
PubChem CID5311007
IUPAC Name(5Z,8Z,11Z,14Z)-N-cyclopropylicosa-5,8,11,14-tetraenamide
Molecular FormulaC23H37NO
Molecular Weight343.5
XLogP6.6
Topological Polar Surface Area29.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count1
Rotatable Bond Count15
Heavy Atom Count25
Formal Charge0
Complexity441
SMILES
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NC1CC1
InChI
InChI=1S/C23H37NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(25)24-22-20-21-22/h6-7,9-10,12-13,15-16,22H,2-5,8,11,14,17-21H2,1H3,(H,24,25)/b7-6-,10-9-,13-12-,16-15-
InChIKey
GLGAUBPACOBAMV-DOFZRALJSA-N
Chemical Structure
2D Structure
2D structure of Arachidonylcyclopropylamide
CAS: 229021-64-1
CID: 5311007
Formula: C23H37NO
MW: 343.5
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight343.5
XLogP36.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count1
Rotatable Bond Count15
Exact Mass343.287514804
Monoisotopic Mass343.287514804
Topological Polar Surface Area29.1 Ų
Heavy Atom Count25
Formal Charge0
Complexity441
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count4
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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