Sarcosine
CAT:
804-HY-101037-01
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Sarcosine
- CAS Number: 107-97-1
- UNSPSC Description: Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia[1][2].
- Target Antigen: Endogenous Metabolite; GlyT
- Type: Natural Products
- Related Pathways: Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/Sarcosine.html
- Purity: 98.0
- Solubility: DMSO : < 1 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)
- Smiles: O=C(O)CNC
- Molecular Weight: 89.09
- References & Citations: [1]Katarzyna Socała, et al. Effects of sarcosine, a glycine transporter type 1 inhibitor, in two mouse seizure models. Pharmacol Rep. Mar-Apr 2010;62(2):392-7.|[2]Mei-Yi Lee, et al. Effects of sarcosine and N, N-dimethylglycine on NMDA receptor-mediated excitatory field potentials. J Biomed Sci. 2017; 24: 18.
- Shipping Conditions: Room Temperature
- Storage Conditions: Store at room temperature 3 years
- Clinical Information: Phase 4