Human lactoferrin | Gentaur

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Human lactoferrin

CAT:

399-CSB-NP008701h-02

Size:

1 mg

Price:

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Human lactoferrin

Target: Human lactoferrin
Nature: Native
Source: Purified from human milk
Applications: ELISA, WB, SDS-PAGE
Field of Research: Cardiovascular
Assay Type: Native Protein
Relevance: Lactoferrin is a glycoprotein present in most human mucosal secretions, including human milk. Lactoferrin is bacteriostatic in low iron media and, in some settings, bactericidal. Lactoferrin impairs ability of Shigella flexneri serotype 5 strain M90T to invade HeLa cells. To determine the mechanism by which lactoferrin decreases invasiveness of Shigella organisms, its effect on the major virulence proteins responsible for bacterial uptake by host cells was evaluated. Lactoferrin induced degradation of invasion plasmid antigens IpaB and, to a lesser extent, IpaC, the key proteins responsible for bacteria-directed phagocytosis by mammalian cells.
Purity: >95% (SDS-PAGE)
Bioactivity: Not test
Length: Full length protein
Form: Liquid
Buffer: PBS, pH 7.4
Storage Conditions: Aliquot and store at -20℃ or -80℃. Avoid repeated freeze/thaw cycles.

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