Human Lactoferrin

• Background:

  Transferrins are iron binding transport proteins which can bind two Fe (3+) ions in association with the binding of an anion, usually bicarbonate. Lactotransferrin has antimicrobial activity which depends on the extracellular cation concentration. Lactoferroxins A, B and C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors, while lactoferroxin B and C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors. The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity.

• Gene ID:

  4057

• Swiss Prot:

  P02788

• Expression System:

  Native protein

• Conjugation:

  Unconjugated

• Source:

  Purified native protein

• Applications:

  Others

• Endotoxin:

  Not Tested

• Purity:

  >95% as determined by SDS-PAGE

• Buffer:

  50mM Tris and 0.2 M NaCl (pH 8.0)

• Storage Conditions:

  Stored at -70°C or -20°C. Avoid repeated freeze/thaw cycles.

• Gene ID URL:

  4057