7,15-Dihydroxy-4,4,14-trimethyl-3,11-dioxochol-8-en-24-oic acid

7,15-Dihydroxy-4,4,14-trimethyl-3,11-dioxochol-8-en-24-oic acid

• CAS Number: 942936-54-1
• UNSPSC Description: 7,15-Dihydroxy-4,4,14-trimethyl-3,11-dioxochol-8-en-24-oic acid is one of the ganoderma triterpenoids which have been recognised as an important bioactive ingredient in Ganoderma Lucidum Karst. 7,15-Dihydroxy-4,4,14-trimethyl-3,11-dioxochol-8-en-24-oic acid can be used for the research of various etiologies[1][2].
• Target Antigen: Others
• Type: Natural Products
• Related Pathways: Others
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/7-15-dihydroxy-4-4-14-trimethyl-3-11-dioxochol-8-en-24-oic-acid.html
• Solubility: 10 mM in DMSO
• Smiles: C[C@H](CCC(O)=O)[C@H]([C@]1(C2)C)CC(O)[C@@]1(C)C(C(O)C[C@@]3([H])C(C)(C)C(CC[C@]43C)=O)=C4C2=O
• Molecular Weight: 460.60
• References & Citations: [1]Yue QX, et, al. Interaction of Ganoderma Triterpenes with Docetaxel and Cisplatin in Cytotoxicity against Human Carcinoma Cells. Chinese Journal of Natural Medicines. 2008 Sep; 6 (5): 367-371.|[2]Wu JG, et, al. Hepatoprotective effect of ganoderma triterpenoids against oxidative damage induced by tert-butyl hydroperoxide in human hepatic HepG2 cells. Pharm Biol. 2016;54(5):919-29.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported