Bemegride

• Description :

  Bemegride (3-Ethyl-3-methylglutarimide) is a central nervous system stimulant and antidote for barbiturate poisoning[1][2].

• Product Name Alternative :

  3-Ethyl-3-methylglutarimide; Bemegrid

• UNSPSC :

  12352005

• Hazard Statement :

  H300, H311, H331

• Target :

  GABA Receptor

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/Bemegride.html

• Purity :

  99.96

• Solubility :

  DMSO : ≥ 32 mg/mL

• Smiles :

  O=C(CC(C)(CC)C1)NC1=O

• Molecular Formula :

  C8H13NO2

• Molecular Weight :

  155.19

• Precautions :

  H300, H311, H331

• References & Citations :

  [1]Mistry DK, et al. Actions of steroids and bemegride on the GABAA receptor of mouse spinal neurones in culture.Exp Physiol, 1990, 75 (2),199-209.|[2]Arblaster CI, et al. Studies on the development of physical dependence on barbitone in the rat and rat atrium. Farmaco Sci. 1986 Jan, 41 (1), 3-22.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Launched

• CAS Number :

  [64-65-3]