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Caspase-8/CASP8 Rabbit Polyclonal Antibody

CAT: 0013-GTR17689967Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR17689967Size:100 µg
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Description
Caspase-8/CASP8 Rabbit Polyclonal Antibody
Product Name Alternative
Caspase-8; CASP-8; 3.4.22.61; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; MACH; Caspase-8 subunit p18; Caspase-8 subunit p10; CASP8; MCH5
UniProt
Q14790
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human Caspase-8 (P10) .
Target
Caspase-8
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cancer Biology, Cell Biology, Metabolism Research
Purification
Immunogen affinity purified.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Dilution
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human Western blot, 0.1-0.5μg/ml, Human
Form
Lyophilized
Molecular Weight
45 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
IHC, WB
Host or Source
Rabbit
Preservative
Each vial contains antibody formulated with stabilizing components, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. *This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.
Isotype
Rabbit IgG

UniProtKB · Q14790

Caspase-8

CASP8_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q14790
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CASP8
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
CASP-8
EC number
3.4.22.61
Processing
Precursor
Secondary accessions
O14676, Q14791, Q14792, Q14793, Q14794, Q14795, Q14796, Q15780, Q15806, Q53TT5, Q8TDI1, Q8TDI2, Q8TDI3, Q8TDI4, Q8TDI5, Q96T22, Q9C0K4, Q9UQ81
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationPhosphoproteinZymogen

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisHost-virus interaction

Cellular component

Cell projectionCytoplasmNucleus

Disease

Disease variant

Molecular function

HydrolaseProteaseThiol protease

Domain

Repeat

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