QM-FN-SO3

QM-FN-SO3

• CAS Number: 2316820-94-5
• UNSPSC Description: QM-FN-SO3 is a BBB-penetrable near-infrared (NIR) aggregation-induced emission (AIE)-active probe for Aβ plaques. QM-FN-SO3 can be used for in vivo detection of Aβ plaques. QM-FN-SO3 has ultra-high S/N ratio, binding affinity, and high-performance NIR emission[1].
• Target Antigen: Amyloid-β; Fluorescent Dye
• Type: Dye Reagents
• Related Pathways: Neuronal Signaling;Others
• Applications: Neuroscience-Neurodegeneration
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/qm-fn-so3.html
• Solubility: 10 mM in DMSO
• Smiles: N#C/C(C#N)=C1C=C(N(CCCS(=O)(O[Na])=O)C2=C\1C=CC=C2)/C=C/C3=CC=C(C4=CC=C(N(C)C)C=C4)S3
• Molecular Weight: 564.65
• References & Citations: [1]Wei Fu, et al. Rational Design of Near-Infrared Aggregation-Induced-Emission-Active Probes: In Situ Mapping of Amyloid-β Plaques with Ultrasensitivity and High-Fidelity. J Am Chem Soc. 2019 Feb 20;141(7):3171-3177.|[2]Wei Fu, Wei-Hong Zhu, et al. Rational Design of Near-Infrared Aggregation-Induced-Emission-Active Probes: In Situ Mapping of Amyloid-β Plaques with Ultrasensitivity and High-Fidelity. J. Am. Chem. Soc. 2019, 141, 7, 3171–3177.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported