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LXQ-217

CAT: 0804-HY-161360Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-161360Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LXQ-217 is an oral active SHP2 inhibitor with the IC50 of 2.01 μM. LXQ-217 induces apoptosis and inhibits cell growth in vivo and in vitro[1].
CAS Number
2524718-79-2
UNSPSC
12352005
Target
Apoptosis; SHP2
Type
Reference compound
Related Pathways
Apoptosis; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lxq-217.html
Solubility
10 mM in DMSO
Smiles
CCOC(C=C1)=CC=C1OC2=CC=C(C3=NN(C=O)C(C4=C(Br)C(Br)=C(O)C(O)=C4)C3)C=C2
Molecular Formula
C24H20Br2N2O5
Molecular Weight
576.23
References & Citations
[1]Sun H, et al. Small Molecule SHP2 Inhibitor LXQ-217 affects Lung Cancer Cell Proliferation in Vitro and in Vivo. Chem Biodivers. Published online February 20, 2024.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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