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Human TNF α converting enzyme, TACE ELISA Kit

CAT: 0399-CSB-E09315h-01Size: 48 TestsDry Ice: NoHazardous: No
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CAT#:0399-CSB-E09315h-01Size:48 Tests
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Product Name Alternative
ADAM17; CSVP; TACE; Disintegrin and metalloproteinase domain-containing protein 17; ADAM 17; Snake venom-like protease; TNF-alpha convertase; TNF-alpha-converting enzyme; CD antigen CD156b
Abbreviation
ADAM17
UniProt
P78536
Reactivity
Homo sapiens
Target
ADAM metallopeptidase domain 17
Type
Sandwich
Field of Research
Signal Transduction
Wavelength
450 nm
Assay Principle
Quantitative
Assay Performance Time
1-5h
Sample Type
Serum, Plasma, Tissue Homogenates, Cell Lysates
Sample Volume
50-100 µL
Detection Range
62.5 pg/mL - 4000 pg/mL
Sensitivity
15.6 pg/mL

UniProtKB · P78536

Disintegrin and metalloproteinase domain-containing protein 17

ADA17_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P78536
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ADAM17
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
ADAM 17
EC number
3.4.24.86
Processing
Precursor
Secondary accessions
O60226
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembrane

PTM

Cleavage on pair of basic residuesDisulfide bondGlycoproteinPhosphoproteinUbl conjugationZymogen

Disease

Disease variantHypotrichosis

Molecular function

HydrolaseMetalloproteaseProtease

Ligand

Metal-bindingZinc

Biological process

Notch signaling pathway

Domain

SH3-bindingSignalTransmembraneTransmembrane helix

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