RTC-5
CAT:
804-HY-123952-01
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
RTC-5
- Product Name Alternative: TRC-382
- CAS Number: 1423077-49-9
- UNSPSC Description: RTC-5 (TRC-382) is an optimized phenothiazine with anti-cancer potency. RTC-5 demonstrates efficacy against a xenograft model of an EGFR driven cancer, its effects is attributed to concomitant negative regulation of PI3K-AKT and RAS-ERK signaling[1].
- Target Antigen: EGFR
- Type: Reference compound
- Related Pathways: JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/rtc-5.html
- Purity: 99.89
- Solubility: DMSO : 15 mg/mL (ultrasonic)
- Smiles: O=S(C1=CC=C(OC(F)(F)F)C=C1)(NCCCN2C3=CC(Cl)=CC=C3CCC4=CC=CC=C42)=O
- Molecular Weight: 510.96
- References & Citations: [1]Kastrinsky DB, et al. Reengineered tricyclic anti-cancer agents. Bioorg Med Chem. 2015 Oct 1;23(19):6528-34.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported