Albenatide

CAT: 0804-HY-120828Size: InquireDry Ice: NoHazardous: No

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CAS Number

1031700-39-6

UNSPSC Description

Albenatide (CJC 1134PC) is a modified Exendin-4 (HY-13443) analogue conjugated to human recombinant albumin (HRA) in vitro to form a long-acting DPP-4-resistant GLP-1R agonist. Albenatide covalently binds through a low-molecular chemical linker (cys-C13H19O6N3-lys) to the cysteine residue in position 34 of HRA. Albenatide increases cyclic AMP (cAMP) production in vitro. Albenatide reduces glucose excursions, food intake, gastric emptying in wild-type mice and improves glucose tolerance and reduces body weight in high-fat diet mice[1].

Target Antigen

GLP Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/albenatide.html

Smiles

[Albenatide]

References & Citations

[1]Mikkel Christensen, et al. Once-weekly GLP-1 agonists: How do they differ from exenatide and liraglutide? Curr Diab Rep. 2010 Apr;10(2):124-32.

Shipping Conditions

Room temperature

Clinical Information

Phase 2

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TP2368-01	Albenatide

Albenatide

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