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Flumorph

CAT: 0804-HY-17521-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-17521-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Flumorph (SYP-L190) is a carboxylic acid amide (CAA) fungicide. IC50 value: Target: Fungicide agent Flumorph did not inhibit the synthesis of cell wall materials, but disturbed the polar deposition of newly synthesized cell wall materials during cystospore germination and hyphal growth. In flumorph-treated hyphae, the most characteristic change was the development of periodic swelling ("beaded" morphology) and the disruption of tip growth. Upon removing flumorph, normal tip growth and organized F-actin were observed again [1]. Flumorph had induced systemic genotoxicity in mammals as it caused DNA damage in all tested vital organs, especially in brain and spleen [2].
CAS Number
211867-47-9
Product Name Alternative
SYP-L190
UNSPSC
12352005
Target
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Flumorph.html
Purity
99.57
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N1CCOCC1)/C=C(C2=CC=C(OC)C(OC)=C2)\C3=CC=C(F)C=C3
Molecular Formula
C21H22FNO4
Molecular Weight
371.40
References & Citations
[1]Sheng Zhu S, et al. Flumorph Is a Novel Fungicide That Disrupts Microfilament Organization in Phytophthora melonis. Phytopathology. 2007 May;97 (5) :643-9.|[2]Zhang T, et al. Assessment of genotoxic effects of flumorph by the comet assay in mice organs. Hum Exp Toxicol. 2014 Mar;33 (3) :224-9.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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