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Ki16198

CAT: 0804-HY-18641-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-18641-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ki16198 is a potent and orally active LPA receptor antagonist, the methyl ester of Ki16425. Ki16198 inhibits LPA1 and LPA3-induced inositol phosphate production with Ki values of 0.34 μM and 0.93 μM, respectively. Ki16198 is effective for pancreatic cancer tumorigenesis and metastasis in vivo[1].
CAS Number
355025-13-7
UNSPSC
12352005
Target
LPL Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ki16198.html
Purity
98.17
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(OC)CCSCC1=CC=C(C2=C(NC(OC(C3=CC=CC=C3Cl)C)=O)C(C)=NO2)C=C1
Molecular Formula
C24H25ClN2O5S
Molecular Weight
488.98
References & Citations
[1]Mayumi Komachi, et al. Orally active lysophosphatidic acid receptor antagonist attenuates pancreatic cancer invasion and metastasis in vivo. Cancer Sci. 2012 Jun;103 (6) :1099-104.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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B1591-SKi16198
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A11966-10Ki16198 10mg

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