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Hexokinase, microorganism

CAT: 0804-HY-P2776Size: 1 KUDry Ice: NoHazardous: No
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CAT#:0804-HY-P2776Size:1 KU
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Description
Hexokinase (ScHEX1) (EC 2.7.1.1) is a glycolytic enzyme hexokinase that is inhibited by n-acetylglucosamine. Inhibition of Hexokinase (ScHEX1) by n-acetylglucosamine leads to its separation from the mitochondrial outer membrane, resulting in activation of NLRP3 inflammasome[1].
CAS Number
9001-51-8
UNSPSC
12352204
Hazard Statement
H315-H319-H335
Target
Endogenous Metabolite
Type
Enzyme
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/hexokinase-microorganism.html
Solubility
10 mM in DMSO
Smiles
[Hexokinase,microorganism]
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501
References & Citations
[1]Wolf AJ, et al. Hexokinase Is an Innate Immune Receptor for the Detection of Bacterial Peptidoglycan. Cell. 2016 Jul 28;166 (3) :624-636.
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20°C for 2 years
Scientific Category
Enzyme
Clinical Information
No Development Reported

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