Mouse anti Mouse p27

• Background:

  The p27 kip1 functions as a negative regulator of G1 mouse expression and has been proposed to function as a possible mediator of TGF induced G1 arrest.

• Synonyms:

  p27Kip1, Cyclin-dependent kinase inhibitor p27, Cyclin-dependent kinase inhibitor 1B

• UniProt:

  P46527 (Human), P46414 (Mouse), O08769 (Rat), Q6SLL5 (Dog)

• Host:

  Mouse

• Species Reactivity:

  Human, Mouse, Rat, Dog

• Isotype:

  IgG1

• Clone:

  DCS72

• Conjugation:

  Unconjugated

• Type:

  Monoclonal Antibody

• Source:

  The immunogen for the anti-mouse p27 was a his-tagged recombinant full length mouse p27 protein recognizing a 27kDa protein.

• Applications:

  WB, IP, IHC (paraffin)

• Field of Research:

  Cell Cycle

• Purification Method:

  Ammonium Sulfate Precipitation

• Assay Principle:

  Western Blot (5-10 µg/mL), Immunohistochemistry, Immunoprecipitation (co-precipitates cdk4)

• Stability:

  See expiration date on vial

• Concentration:

  See vial for Concentration

• Form:

  Provided as solution in phosphate buffered saline with 0,08% sodium azide

• Precautions:

  This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving Humans or animals.

• Shipping Conditions:

  Ambient Temperature

• Storage Conditions:

  Product should be stored at -20ºC; Aliquot to avoid freeze/thaw cycles

• Functional Analysis:

  WB

• CAS Number:

  9007-83-4