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Amorphadiene

CAT: 0804-HY-W585869-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W585869-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Amorphadiene is the precursor to the antimalarial agent artemisinin, which is produced through the amorphadiene synthase (ADS) -catalyzed cyclization of farnesyl pyrophosphate (FPP) yeast[1][2].
CAS Number
92692-39-2
UNSPSC
12352211
Hazard Statement
H302-H315-H319-H335
Target
Parasite
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/amorphadiene.html
Smiles
CC([C@H]1[C@]2([H])[C@](CCC(C)=C2)([H])[C@@H](CC1)C)=C
Molecular Formula
C15H24
Molecular Weight
204.35
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Westfall PJ, et al. Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to the antimalarial agent artemisinin. Proc Natl Acad Sci U S A. 2012 Jan 17;109 (3) :E111-8.|[2]Pramastya H, et al. High level production of amorphadiene using Bacillus subtilis as an optimized terpenoid cell factory. N Biotechnol. 2021 Jan 25;60:159-167.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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