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Xanthotoxol (Standard)

CAT: 0804-HY-30152R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-30152R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Xanthotoxol (Standard) is the analytical standard of Xanthotoxol. This product is intended for research and analytical applications. Xanthotoxol (8-Hydroxypsoralen) It is a kind of fragrant bean substance, and it is a CYP450 inhibitor. Xanthotoxol has anti-inflammatory, anti-inflammatory, and 5-HT antagonistic and protective effects. Xanthotoxol inhibited CYP3A4 sum CYP1A2 IC50s separation 7.43 μM sum 27.82 μM. Xanthotoxol can pass through MAPK and NF-κB, inhibiting inflammation[1][2][3][4].
CAS Number
2009-24-7
Product Name Alternative
8-Hydroxypsoralen (Standard)
UNSPSC
12352005
Target
5-HT Receptor; Endogenous Metabolite; Reactive Oxygen Species (ROS) ; Reference Standards
Type
Reference Standards
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB; Others
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/xanthotoxol-standard.html
Smiles
O=C1OC(C(C=C1)=C2)=C(O)C3=C2C=CO3
Molecular Formula
C11H6O4
Molecular Weight
202.16
References & Citations
[1]Ma Z, et al. Metabolism and Metabolic Inhibition of Xanthotoxol in Human Liver Microsomes. Evid Based Complement Alternat Med. 2016;2016:5416509.|[2]Ma Z, et al. Metabolism and Metabolic Inhibition of Xanthotoxol in Human Liver Microsomes. Evid Based Complement Alternat Med. 2016;2016:5416509.|[3]He W, et al. Xanthotoxol exerts neuroprotective effects via suppression of the inflammatory response in a rat model of focal cerebral ischemia. Cell Mol Neurobiol. 2013 Jul;33 (5) :715-22.|[4]Lee Y, et al. Anti-Inflammatory Effects of Psoralen Derivatives on RAW264.7 Cells via Regulation of the NF-κB and MAPK Signaling Pathways. Int J Mol Sci. 2022 May 22;23 (10) :5813.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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TB0655Xanthotoxol
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301127Xanthotol (Xanthotoxol)
A14771-100Xanthotoxol 100mg
A14771-25Xanthotoxol 25mg
A14771-10Xanthotoxol 10mg
A14771-5Xanthotoxol 5mg

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