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Bestim

CAT: 0804-HY-122357-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-122357-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bestim (γ-Glu-Trp) is a dipeptide, which exhibits high affinity to murine peritoneal macrophages, thymocytes, and plasma membranes isolated from these cells, with Kds of 3.1, 2.1, 18.6 and 16.7 nM, respectively. Bestim inhibits adenylate cyclase in the membranes of murine macrophages and thymocytes. Bestim exhibits immunomodulatory efficacy[1].
CAS Number
66471-20-3
Product Name Alternative
γ-Glu-Trp
UNSPSC
12352209
Target
Adenylate Cyclase
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/bestim.html
Purity
98.73
Solubility
10 mM in DMSO
Smiles
O=C([C@@H](NC(CC[C@H](N)C(O)=O)=O)CC1=CNC2=C1C=CC=C2)O
Molecular Formula
C16H19N3O5
Molecular Weight
333.34
References & Citations
[1]Kolobov AA, et al., Interaction of the synthetic immunomodulatory dipeptide bestim with murine macrophages and thymocytes. Bioorg Khim. 2008 Jan-Feb;34 (1) :43-9. Russian.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

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