DBCO-NHCO-PEG6-Biotin

DBCO-NHCO-PEG6-Biotin

• UNSPSC Description: DBCO-NHCO-PEG6-Biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-NHCO-PEG6-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
• Target Antigen: PROTAC Linkers
• Type: Reference compound
• Related Pathways: PROTAC
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/dbco-nhco-peg6-biotin.html
• Smiles: O=C(CCNC(CCOCCOCCOCCOCCOCCOCCNC(CCCC[C@H]1SCC(N2)C1NC2=O)=O)=O)N(C3)C4=C(C=CC=C4)C#CC5=C3C=CC=C5
• Molecular Weight: 838.02
• References & Citations: [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
• Shipping Conditions: Blue Ice